Alzheimer: dipende da un errato meccanismo cellulare?
Alla base delle più diffuse forme di demenza, malattia di Alzheimer compresa, ci potrebbe essere un problema alla via endo-lisosomiale della cellula, di cui rappresenta il “sistema digerente”. A ipotizzarlo è una ricerca condotta dall’Irccs Centro San Giovanni di Dio Fatebenefratelli di Brescia insieme all’Irccs Istituto Neurologico Carlo Besta di Milano e all’Università di Anversa (Belgio). La via endo-lisosomiale presiede anche alla “gestione” delle proteine e un suo cattivo funzionamento potrebbe favorirne l’accumulo a livello del cervello, come accade per la beta amiloide nel caso della malattia di Alzheimer. (www.pixabay.com)
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